Support of Affymetrix GeneChip® Exon arrays (for the gene expression use case) You can now upload transcript IDs from all probes that map to genes. This allows you to interpret Exon chip data in the context of the biological pathways, processes, and networks that are part of the Ingenuity Knowledge Base. Support of new species with EntrezGene Ids Cow Chimp Chicken Rhesus macaque monkey Plant (Arabidopsis thaliana) Yeast (Saccharomyces cerevisiae) Fly (Drosophila melanogaster) Worm (Caenorhabditis elegans) Zebrafish (Danio rerio)

You now analyze data from nine new relevant species through the direct mapping to the human, rat, or mouse orthologs. Researchers can now avoid the time-consuming and manual mapping process formerly needed for analyzing data sets from these animal models. Predicted pathway modeling of data generated from these species enables biological interpretation. IPA supports the mapping of Entrez Gene ID's,GenBank, Refseq, and GenPept ID's. In addition, microarray ID mapping is supported for a subset of the new species.

• Compare Feature
  
  You can use these simple tools to easily identify commonalities or differences across sets of molecules in gene lists, pathways, biomarker sets, and customized lists generated from IPA analyses. This convenient tool facilitates your understanding of the role of different molecules in different disease types, pathways, or networks.
  
  
  
  
• Content
  
  The summer release of IPA includes content updates for:
  
  
  • Drug information such as manufacturer, clinical trial sponsor, date of last clinical trial update, and link to NCT website
  • Protein-protein interactions Additional Protein-Protein Interaction Content based on external database imports, >80K findings, includes: BIND, DIP, MIPS, IntAct, Biogrid, MINT, Interactome studies (Y2H)
    
  • New canonical pathways:
    
    
    • 14-3-3-mediated Signaling
    • Alpha-Adrenergic Signaling
    • Erythropoietin Signaling
    • RAR Activation
    • Role of BRCA1 in DNA Damage Response
    • BMP Signaling
      
      
• Filtering on Data Source
  
  New protein interaction content is available from various sources such as such as BIND, BIOGRID, MINT, MIPS, INTACT, DIP, and interactome studies, and you can now filter on selected data source at both the pre- and post- analysis stage.
  
  

  Pre-analysis: Search and explore disease, pathway, and network-specific biological concepts in the context of other high-quality databases.

  Post analysis: Explore your analysis results further using My Pathway tools now with the option to select data base source.

• Reference Management
  
  You can easily export your references directly into Endnote, BibTeX, or PlainText formats. This enables you to organize, build, and search through process-, pathway-, or network-specific reference libraries, eliminating the time-consuming step of manually searching through bibliographies when preparing manuscripts.